abstract |
A compound represented by the formula (see formula) and pharmaceutically acceptable solvates and salts of said compound are described, wherein: the single dotted line = between the ring carbons to which R1 degree and R34 are attached represents either a single bond or a double bond; the double dotted line between X and the carbon to which Y is attached represents either a single bond or an absent link; X is -O- or -NR6- when the double dotted line represents a single link; X is H, -OH or - NHR20 when the double dotted line represents an absent link; and other parameters are described as defined in this application; In addition, pharmaceutical compositions and combinations containing said compounds and their uses as thrombin receptor antagonists and cannabinoid receptor binding compounds are described. |