| abstract |
Anti-CD148 antibodies and antigen binding region thereof, as well as pharmaceutical compositions comprising such antibodies and antigen binding regions, are described. Methods for using such antibodies and antigen binding regions to bind CD148 epitopes and activate CD148 function, such as inhibition of angiogenesis, are also described. Epitopes that can be used to activate CD148 function and anti-angiogenesis activity are also described, as well as methods to identify compounds that can bind them. |