http://rdf.ncbi.nlm.nih.gov/pubchem/patent/MX-PA06010950-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5f8f2f2078036141fa6aa96332570c85 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S977-717 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S977-911 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5123 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-51 |
| filingDate | 2005-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c1380a6f02d5507f76059b71586088b9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0309986bc1ec30c2acef9305f51890c8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_36eb6effc37be86c116c397f86279282 |
| publicationDate | 2007-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | MX-PA06010950-A |
| titleOfInvention | FORMULATIONS IN NANO-PARTICLES OF PLATINUM COMPOUNDS. |
| abstract | Solid Lipid Nanoparticles of platinum compound compounds, particularly antitumor platinum complexes, are described. The nonoparticles of the invention are obtained by means of a process comprising a) preparing a first microemulsion by mixing a molten lipid, a surfactant, and optionally a co-surfactant and the aqueous solution of platinum compound; b) preparing a solution by mixing a surfactant and optionally a co-surfactant in water, heating to complete solution, preferably at the same melting temperature of the lipid used in a) and adding a co-surfactant; c) dispersing the microemulsion obtained in a) in the solution obtained in b) obtaining a multiple microemulsion c); d) dispersing the microemulsion obtained in c) in aqueous medium at a temperature ranging from 0.5 degree C to 4 degree C obtaining a dispersion of solid lipid microspheres; e) wash the lipid microspheres obtained in d) with an aqueous medium through ultrafiltration and freeze-dry, optionally in the presence of a loading agent and a cryoprotective agent. |
| priorityDate | 2004-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 56.