| abstract |
The invention provides new isomers of dihydrotetrabenazine, individual enantiomers and mixtures thereof wherein dihydrotetrabenazine. Methods are also provided for the preparation of the new isomers, pharmaceutical compositions containing them and their use in the treatment of hyperkinetic movement disorders such as Huntington's disease, hemiballismus, senile chorea, tic, tardive dyskinesia and Tourette syndrome. |