http://rdf.ncbi.nlm.nih.gov/pubchem/patent/MX-PA06005688-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9253fd2c7009fb8cd0efa451055c7ab2 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0078 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0048 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-127 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127 |
filingDate | 2004-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3c19779618fd2eb12f59e71269a0fffa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0e2645c8d751278886c1333fe3e5b2ca http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a13c8183603c572aec8771c60535989a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_30477cd1172c726de2332b003512312a |
publicationDate | 2006-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | MX-PA06005688-A |
titleOfInvention | STABLE LIPOSOMA COMPOSITIONS THAT INCLUDE A LIPOPHILIC AMINE CONTAINING PHARMACEUTICAL AGENTS. |
abstract | A stable liposome composition for delivering a pharmaceutical agent, the composition comprises: (a) a suitable aqueous medium; (b) liposomes formed from a suitable phospholipid; (c) at least one pharmaceutical agent being at least partially encapsulated in the liposomes, and which is selected from: (i) a lipophilic amine and a pharmaceutically acceptable acid, wherein the pharmaceutically acceptable acid is selected from an organic acid or inorganic, and (ii) a pharmaceutically acceptable organic acid salt of a lipophilic amine, and optionally a pharmaceutically acceptable organic acid; wherein the amount of the pharmaceutically acceptable acid present in the composition is such that the pH of the liposome composition is less than or approximately equal to the pKa of the amino group of the pharmaceutically active lipophilic amine. Compositions, equipment and methods for the preparation thereof, as well as methods for further improving the stability of the composition by autoclaves, and methods for the identification of stable liposome compositions of the present invention are also provided. |
priorityDate | 2003-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 370.