| abstract |
Compounds of the formula (I) (see formula (I)): characterized in that: R 1 represents a group selected from a hydrogen, methyl, methoxy, hydroxy, amino, dimethylamino, acetamide, pyrrolidin-1-yl and hydroxymethyl atom; R2 represents a group selected from phenyl, pyridyl, pyrimidyl, quinolyl, isoquinolyl, indolyl, pyrolyl, [1,2,3] -triazolyl, benzo [c] isoxazolyl, thienyl, pyrazolyl, isothiazolyl, imidazolyl, benzofuranyl, pyrazolo [5, 1-c] [1,2,4] triazyl, each of these groups being optionally substituted with 1 to 3 groups, the same or different independently from each other, selected from halogen, trifluoromethyl, C1-C4 alkyl, C1 alkoxy -C4, hydroxy, amino, acetamide, tert-butyloxycarbonylamino, cycloalkylcarbonylamino, sulfonamide, nitro, acetylmethoxy, cyclopentyloxy; and optionally, its optical isomers, and addition salts thereof with a pharmaceutically acceptable acid or base. |