abstract |
The present invention is directed to alkanyl and cycloalacanoyl amine derivatives, compositions containing these derivatives, and methods of their use for the prevention and treatment of conditions relieved by the reabsorption of monoamine including, inter alia, vasomotor symptoms (VMS for their acronym in English), sexual dysfunction, gastrointestinal and genitourinary disorders, chronic fatigue syndrome, fibromyalgia syndrome, nervous system disorders and combinations thereof, particularly those conditions selected from the group consisting of major depressive disorder, vasomotor symptoms, urinary incontinence of impulse and tension, fibromyalgia, pain, diabetic neuropathy and combinations thereof. |