Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_24e76490bed88751680a5fef9bc73892 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-506 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D409-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-506 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-04 |
filingDate |
2004-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fab28e3a1dc8eaabd2137b7ab01804fb |
publicationDate |
2006-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
MX-PA06003207-A |
titleOfInvention |
5-ARILPIRIMIDINAS AS ANTI-CANCER AGENTS. |
abstract |
This invention relates to certain 5-arylpyrimidine compounds or a pharmaceutically acceptable salt thereof, and compositions containing these compounds or a pharmaceutically acceptable salt thereof, wherein the compounds are anti-cancer agents useful for the treatment of cancer. in mammals. This invention also relates to a method for treating or inhibiting the growth of cancer tumor cells and associated diseases in a mammal and also provides a method for the treatment or prevention of cancerous tumors that express resistance to multiple drugs (MDR) or are resistant. due to MDR, in a mammal in need of the same method which comprises administering the mammal an effective amount of the compounds or a pharmaceutically acceptable salt thereof. More specifically, the present invention relates to a method of treatment or inhibition of the growth of cancer tumor cells and associated diseases in a mammal in need thereof by promoting microtubule polymerization comprising administering to the mammal an effective amount of the compounds and pharmaceutically acceptable salts thereof. |
priorityDate |
2003-09-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |