abstract |
The present invention describes compounds of formula I (see formula) in which Ar, X, R1 and R11 are as defined herein, said compounds are novel antagonists for melanin concentrating hormone (MCH), as well as methods for preparing said compounds; In another embodiment, the invention describes pharmaceutical compositions comprising said MCH antagonists, as well as methods for their use to treat obesity, metabolic disorders, eating disorders, such as hyperphagia and diabetes. |