abstract |
The invention provides a novel class of compounds, pharmaceutical compositions comprising said compounds and methods for using said compounds to treat or prevent diseases or disorders associated with abnormal or unregulated kinase activity, in particular diseases or disorders that involve abnormal activation. of Abl, BCR-Abl, Bmx, c-Raf, Csk, Fes, FGFR, Flt3, Ikk, IR, JNK, Lck, Mkk, PKC, PKD, Rsk, SAPK, Syk, Trk, BTK, Src, EGFR kinases , IGF, Mek, Ros and Tie2. |