| abstract |
A seric cholesterol lowering agent or preventive or therapeutic agent for atherosclerosis, which comprises a combination of a compound represented by the following general formula (I) or pharmaceutically acceptable salts thereof with a cholesterol biosynthesis inhibitor and / or a cholesterol lowering agent of the fibrous type. (I) (b) (a) (in formula A1, A2, A3, and A4 each which is hydrogen, a group represented by formula (b), or a group represented by formula (A), with the provided that at least one of these is a group represented by formula (a); A2 is C1-5 alkyl etc; and n, p, q and r is each an integer of 0, 1 or 2 (see formula (I )). |