http://rdf.ncbi.nlm.nih.gov/pubchem/patent/MX-PA05013811-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6572ff5df928fd17340eb2a8cb6d8502 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-13 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-404 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-42 |
filingDate | 2004-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f44443e0f024a963e3d985b7fcdbc37 |
publicationDate | 2006-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | MX-PA05013811-A |
titleOfInvention | NEW CRYSTAL FORMS OF PERINDOPRIL ERBUMINA. |
abstract | Two novel crystalline forms (and (of perindopril erbumine, which are appropriate as therapeutic substances in drugs used to treat cardiovascular diseases, especially high blood pressure and heart failure) are described. The crystalline form (obtained by crystallizing perindopril erbumine from MTBE that Contains from 1.5 to 2.5% (v / v) of water at between 30 and 45 degrees C, preferably from 34 to 45 degrees C, crystallization takes place in a timely manner by agitation The form (crystalline changes to form (crystalline if the water, practically by azeotropic distillation, preferably from 35 to 37 degree C, and stirring continues for at least 15 hours from 30 to 45 degree C, preferably from 35 to 37 degree C. The form (crystalline can also be obtained by stirring the form ( or (crystalline in tert-butyl methyl ether containing 0.9 to 1.4% (v / v) of water, from 33 to 38 degrees C, while inoculating the same ma with the form (crystalline. The (crystalline form can also be obtained by stirring the form (or (crystalline in tert-butyl methyl ether containing 0.9 to 1.4% (v / v) water, from 28 to 35 degree C, while inoculating it with the form (crystalline, or stirring the form (or (crystalline in tert-butyl methyl ether with 1.5 to 2.0% (v / v) water content, from 35 to 38 degrees C. |
priorityDate | 2003-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 44.