http://rdf.ncbi.nlm.nih.gov/pubchem/patent/MX-PA05013452-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-067 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-14 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-067 |
| filingDate | 2004-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_22d035e790f06f2284f3972c207dbbc9 |
| publicationDate | 2006-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | MX-PA05013452-A |
| titleOfInvention | PROCESS TO PREPARE DERIVATIVES OF 4'-AZIDONUCLEOSIDE. |
| abstract | A process for the preparation of a 4O-azido-2O, 3O, 5O-triacyl nucleoside compound (I: B = B; R1 is R1aCO- and R2 is R2aCO-) or a 4O-azidonucleoside compound (I; B is B1 or B2 and R1 and R2 are hydrogen and the acid addition salts thereof) wherein R1a and R2a are independently alkyl of 1 to 10 carbon atoms or phenyl optionally substituted with 1 to 3 substituents selected from the group consisting of alkyl, alkoxy, halogen, nitro or cyano and R3 is selected from the group consisting of hydrogen, alkyl of 1 to 6 carbon atoms, haloalkyl of 1 to 3 carbon atoms and halogen, which comprises contacting a compound of 5O- iodine II with a peracide, R2aC (O) OOH, an acid R2aC (O) OH and a phase transfer catalyst and interconverting a uridine B1 to a cytosine B2. The present process provides 4azidonucleosides safely and selectively with high purity and increased efficiency. |
| priorityDate | 2003-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 25.