| abstract |
Pharmaceutically acceptable salts of the compounds of the following formula are inhibitors of poly (ADP-ribosyl) transferase (abbreviated in English PARP), and are useful as therapeutic agents in the treatment of cancers and in the relief of the effects of stroke , head trauma, and neurodegenerative disease; The compounds of the invention can be used as therapeutic agents against cancer, for example in combination with cytotoxic and / or radiation agents. |