| abstract |
This invention provides new compounds, pharmaceutical compositions and diagnostic equipment comprising such compounds, and methods of using such compounds to inhibit the activity of the NAALADase enzyme, detecting diseases in which the NAALADase levels are altered, inhibiting angiogenesis, performing an activity of TGF- (or a neuronal activity, and treat a glutamate abnormality, a seizure disorder, neuropathy, pain, a prostate disease, cancer, Huntington's disease, diabetes, a retinal disorder or glaucoma. |