abstract |
This invention provides biphenyl derivatives of formula I, (see formula (I)), wherein R1, R2, R3, R4, R5, R6, R7, W, a, b, and c are as defined in the specification, or a pharmaceutically acceptable salt or solvate or stereoisomer thereof. The biphenyl derivatives of this invention possess both an agonist activity of the adrenergic receptor (2 as an antagonist of the muscarinic receptor and therefore, such as biphenyl derivatives, are useful for treating pulmonary disorders, such as chronic obstructive pulmonary disease and asthma. |