http://rdf.ncbi.nlm.nih.gov/pubchem/patent/MX-PA05008298-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1394e66eb648f9bf0a1f5507fe25b67b |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7034 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-277 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D317-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C255-37 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C255-37 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7034 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-277 |
filingDate | 2004-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1f05e97acf0c27059d5c806796cd990d |
publicationDate | 2005-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | MX-PA05008298-A |
titleOfInvention | INHIBITOR OF THE BREAST CANCER RESISTANCE PROTEIN. |
abstract | The invention provides a drug which inhibits BCRP; a breast cancer resistance protein inhibitor that contains, as an active ingredient, a diphenylacrylonitrile derivative represented by the following formula (1): (see formula (1)) [where, each of the 8 R's, the which are the same or different from each other, represents a hydrogen atom, a hydroxyl group, a nitro group, an amino group, an acetylamino group (-NHCOCH3 group), a cyano group (-CN group), a formyl group ( group -CHO), -COOR1 (R1 is hydrogen or C1-C4 alkyl), -O (CH2) nCOOR2 (n = 1-7: R2 is hydrogen or C1-C4 alkyl), -OOCCH2CH2COOR3 (R3 is hydrogen, C1-C4 alkyl, (Z) -2- (3,4-dimethoxy-phenyl) -3- (4-hydroxy-phenyl) -acrylonitrile, or glycopyranosyl), a C1-C8 alkoxy group, an alkyl group of C1-C4, a halogen atom, a C1-C4 alkoxy group C1-C4 alkoxy C1-C4 alkoxy, a C2-C8 acyloxy group, a C2-C8 halogenoacyloxy group, a methylenedioxy group, a trifluoromethyl group , a phosphate group (for example, -OP (O) (OH) 2) ou na salt thereof, a sulfate group (for example, -OSO3H) or a salt thereof, a glycopyranosyl group or a salt thereof, a phosphate ester of a glycopyranosyl group or an ester salt, a sulfate ester of a glycopyranosyl group or an ester salt, or a piperidinopiperidinocarbonyloxy] group, an ester thereof, or a salt thereof. |
priorityDate | 2003-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 529.