abstract |
A compound of the formula (I) wherein Ar1, A, R3, xm and are as described herein, and Ar2 is a benzothiazolyl, benzooxalyl, or benzoimidazolyl group or a pharmaceutically acceptable salt thereof (a "Benzoazolylpiperazine Compound" ); the compositions comprise a Benzoazolylpiperazine Compound; and methods to treat or prevent pain, UI, an ulcer, IBD, IBS, an addictive disorder, Parkinson's disease, parkinsonism, anxiety, epilepsy, heart attack, a seizure, a pruritic condition, psychosis, a cognitive disorder, loss of memory, restricted brain function, Huntington's chorea, amyotrophic lateral sclerosis, dementia, retinopathy, a muscle spasm, a migraine, vomiting, dyskinesia or depression in an animal that comprises administering to an animal in need thereof, an effective amount of a Benzoazolylpiperazine compound are described. |