| abstract |
The present invention provides a medical device, preferably a contact lens, having a core material and an LbL coating containing antimicrobial metal that does not covalently bind to the medical device and can impart greater hydrophilicity to the medical device. The coating containing antimicrobial metal on a contact lens of the invention has high antimicrobial efficacy against microorganisms, including Gram-positive and Gram-negative bacteria and low toxicity, while maintaining the desired volume properties, such as oxygen permeability and ion permeability of the lens material. These lenses are useful as contact lenses for prolonged use. In addition, the invention provides a method for manufacturing a medical device, preferably a contact lens, which has an LbL coating containing antimicrobial metal thereon. |