| abstract |
A pyrimidone derivative represented by formula (I) or a salt thereof, or a solvate thereof or a hydrate thereof as an inhibitor of tau protein kinase 1: (see formula (I)) wherein X represents CH or a nitrogen atom; R1 represents a C1-C12 alkyl group that can be substituted; R2 represents a C1-C8 alkyl group that can be substituted, a benzene ring that can be substituted, a naphthalene ring that can be substituted, an indane ring that can be substituted, a tetrahydronaphthalene ring that can be substituted, or an optionally substituted heterocyclic ring having 1 to 4 heteroatoms that are selected from the group consisting of oxygen atom, sulfur atom, and nitrogen atom, and which has 5 to 10 atoms that constitute the ring in total. |