abstract |
The 1H-indole-1-yl acetic acid derivatives of 3-alkyl or substituted 3-arylalkyl of formula (I) which are useful as inhibitors of plasminogen activator inhibitor (PAI-1) useful for treating fibrinolytic disorders, Compounds have the structure where: R1, R2, R3, R4, R5, R6 and R7 are those defined herein or a pharmaceutically acceptable salt or ester form thereof. (see formula (1)). |