| abstract |
New therapeutically useful tricyclic compounds, their procedures for their preparation and pharmaceutical compositions containing them. These compounds are potent antagonists of leukotriene D4 and therefore are useful in the treatment, prevention or suppression of pathological conditions, diseases and disorders known to be susceptible to improvement by inhibition of the biological effects of leukotriene D4. The new tricyclic compounds respond to the general formula (I) (see general formula (I)) or their pharmaceutically acceptable salts in which: Symbols A1, A2, A3, A4, G1, G2, R1, R2, R3, R4 , m, n, p, y, yz with how they define in memory. |