http://rdf.ncbi.nlm.nih.gov/pubchem/patent/MX-PA05001786-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_05ff905fdc49089f5f25746eaeb40190 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D237-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D237-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 |
| filingDate | 2003-08-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_44d8e22a3325dd01467d166138638db8 |
| publicationDate | 2005-04-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | MX-PA05001786-A |
| titleOfInvention | DERIVATIVES OF AZAISOQUINOLINE AS INHIBITORS OF METALOPROTEINASE OF MATRIX. |
| abstract | This invention provides compounds defined by the Formula or a pharmaceutically acceptable salt thereof, wherein R1, Q, Y, R2, R3, R4, R5 and n are as defined in the specification. The invention also provides pharmaceutical compositions comprising a compound of Formula 1, or a pharmaceutically acceptable salt thereof, as defined in the specification, together with a pharmaceutically acceptable carrier, diluent or excipient; The invention also provides methods for inhibiting an MMP-13 enzyme in an animal, which comprises administering to the animal a compound of Formula 1, or a pharmaceutically acceptable salt thereof; The invention also provides methods for treating a disease mediated by an MMP-13 enzyme in a patient, comprising administering to the patient a compound of Formula 1, or a pharmaceutically acceptable salt thereof, alone or in a pharmaceutical composition; The invention also provides methods for treating diseases such as heart disease, multiple sclerosis, osteoarthritis and rheumatoid arthritis, arthritis other than osteoarthritis or rheumatoid arthritis, heart failure, inflammatory bowel disease, heart failure, age-related macular degeneration, disease chronic obstructive pulmonary, asthma, periodontal diseases, psoriasis, atherosclerosis, and osteoporosis in a patient, comprising administering to the patient a compound of Formula 1, or a pharmaceutically acceptable salt thereof, alone or in a pharmaceutical composition; The invention also provides combinations, which comprise a compound of Formula 1, or a pharmaceutically acceptable salt thereof, together with another pharmaceutically active component as described in the specification. |
| priorityDate | 2002-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 587.