| abstract |
The (2S, 5Z) -2-amino-7- (ethanimidoylamino) -2-methylhept-5-enoic acid is crystallized as a stoichiometric HCL 1.5 anhydrous salt and a quantifiable crystallization method is described. The salt form was characterized and the absolute configuration of the chiral center was confirmed as "S". The (2S, 5Z) -2-amino-7- (ethanimidoylamino) -2-methylhept-5-enoic acid melted significantly and apparently was acceptably non-hygroscopic for use in a pharmaceutical composition. |