abstract |
The present invention relates to novel compounds of formula 1, a process for their preparation and new intermediates prepared therewith, pharmaceutical formulations containing the compounds and the use of the compounds in therapies. In particular, according to the present invention there are potent and selective compounds for the group 1 mGluR receptor and more particularly for mGluR5. Thus, the compounds of the invention are expected to be very suitable for the prevention and / or treatment of disorders mediated by the mGluR5 receptor, such as acute and chronic neurological and psychiatric disorders and acute and chronic pain disorders. |