| abstract |
The present invention provides dihydropyrazolopyridine compounds represented by formula (1): (See Formula) wherein each symbol is as defined in the specification, optically active forms thereof, and pharmaceutically acceptable salts thereof and hydrates thereof; The compounds of the present invention show a selective and strong inhibitory activity on glycogen synthase kinase-3 beta (GSK-3¦), and are useful as medicaments for the prevention and / or treatment of diabetes, diabetic complications and neurodegenerative diseases or as immunopotentiators |