| abstract |
The present invention relates to the fields of molecular biology, virology, immunology and medicine. The invention provides a composition comprising an ordered and repetitive arrangement of antigen or antigenic determinant, and in particular a peptide composition? ° 1-6-VLP. More specifically, the invention provides a composition comprising a virus-like particle and at least one? 1-6 peptide bound thereto. The invention also provides a process for producing conjugates and orderly and repetitive arrangements, respectively. The compositions of the invention are useful in the production of vaccines for the treatment of Alzheimer's disease and as a drug vaccine to prevent or cure Alzheimer's disease and to effectively induce immune responses, in particular antibody responses. In addition, the compositions of the invention are particularly useful for effectively inducing self-specific immune responses within the indicated context. |