abstract |
Selected amines of Formula XIII are described, which are effective for the prophylaxis and treatment of diseases, such as diseases mediated by angiogenesis. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for the prophylaxis and treatment of diseases and other malignancies or conditions that involve cancer and the like. The present invention also relates to processes for making such compounds as well as useful intermediaries in such processes. |