| abstract |
The present invention provides a compound of the formula (I): wherein. R1 and R2 are independently H or alkyl of 1 to 3 carbon atoms: X represents O or (CH2) N, where n is 0.1 or 2, R3 and R4 independently represents H, alkyl of 1 to 3 carbon atoms, - OCH3, -CF3, aryl or halogen; X1 represents O, S, SO2, SO or CH2; R5 and R6 independently represent hydrogen, alkyl of 1 to 6 carbon atoms (including branched alkyl and optionally substituted by one or more halogens or alkoxy of 1 to 6 carbon atoms), or together with the carbon atom to which they are attached form a 3-6 membered cycloalkyl ring; R7 represents a 6-membered phenyl or a heteroaryl group containing 1, 2 or 3 nitrogen atoms wherein the phenyl or heteroaryl group is substituted by 1, 2, or 3 portions selected from the group consisting of halogen, 1 to 6 alkoxy carbon atoms, alkyl of 1 to 6 carbon atoms, CF3, hydroxy, or phenyl (which may be optionally substituted by one or more alkyl of 1 to 3 carbon atoms; -Ocaqluyl of 1 to 3 carbon atoms, CN, acetyl, hydroxy, halogen or CF3). |