http://rdf.ncbi.nlm.nih.gov/pubchem/patent/MX-PA04012731-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5dfc0b033ac4c841466d97a5f28ea32b |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D473-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D473-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D473-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D519-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D473-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-08 |
filingDate | 2003-06-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cc554a0a0b046b5fd13309df878a3750 |
publicationDate | 2005-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | MX-PA04012731-A |
titleOfInvention | NEWS DERIVED FROM BENCIMIDAZOL. |
abstract | The present invention relates to a compound of the formula (1) see formula (1), (wherein A, B, C, and D are independently nitrogen or optionally substituted methine; E is nitrogen, methine or hydroxy substituted methine; n is 0 or 1; T, U, V and W are independently nitrogen or optionally substituted methine; X is - N (SO2R4) -, -N (COR5) - or -CO-; Y is -C (R6) (R7 ) -, -O- or -N (R8) -, provided that compound () 1) is excluded when E is nitrogen, n is 0, X is -CO-, and Y is -O-) and the like, which is useful as an agent for the treatment of various diseases related to NPY, for example, cardiovascular disorders such as angina, acute or congestive heart failure, myocardial infarction, hypertension, nephropathy, electrolyte abnormality, vasospasm, arteriosclerosis, etc .; central nervous system disorders such as bulimia, depression, anxiety, access, epilepsy, dementia, alcoholism pain, withdrawal symptoms, disorders of cardiac rhythms, schizophrenia, memory impairment, sleep disorders, cognitive impairment, etc., metabolic diseases such as obesity, diabetes, hormonal abnormalities, hypercholesterolemia, hyperlipidemia, gout, liver, adipose, etc .; genital or reproductive disorders such as infertility, premature delivery, sexual dysfunction, etc .; gastrointestinal disorders; respiratory disorders, inflammatory diseases or glaucoma and the like, as well as for example, atherosclerosis, hypogonadism, hyperandrogenism, polycystic ovary syndrome, hirsutism, disorders of gastrointestinal motility, gastroesophageal reflux related to obesity, hypoventilation due to obesity (obesity syndrome) Pickwick), sleep apnea, inflammation, systematic inflammation of the vasculature, osteoarthritis, insulin resistance, bronchoconstriction, preference for alcohol, metabolic syndrome, Aizheimer's disease, cardiac hypertropia, left ventricular hypertropia, hypertriglyceridemia, low HDL cholesterol; cardiovascular disorders such as coronary heart disease (CHD), cerebrovascular diseases, attack, peripheral vascular disease, sudden death, gallbladder diseases, cancer (breast, endometrial and colon), suffocation, hyperuricemia, damaged fertility, pain of the lower back, or increased anesthetic risk, and the like. |
priorityDate | 2002-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 46.