| abstract |
The composition consists of a liquid pharmaceutical formulation comprising nicotine in any form for administration essentially to the lungs; the formulation is acidified and / or alkalinized by regulation and / or regulation of pH that provides a tmax of nicotine in arterial blood of a subject within a short period after administration; administration preferably involves spraying an aerosol into the oral cavity for further distribution, essentially to the lungs; A method for manufacturing the formulation is also included, as well as the use of the formulation in therapy, for example, to treat tobacco addition. |