| abstract |
The invention relates to substituted thiophene derivatives of formula (I), wherein R1 to R8 have the meanings as those indicated in the claims. Medications comprising compounds of this type are useful for preventing or treating various diseases. In this way, these compounds can be used, among others, for the treatment of respiratory disorders and snoring, to improve the respiratory tract, for the treatment of serious and chronic diseases, diseases induced by ischemic and / or repercussion events and by events proliferative or fibrotic, for the treatment or prophylaxis of diseases of the central nervous system and lipid metabolism, and diabetes, blood clotting and parasite infection. |