| abstract |
Compounds of formula (I), defining the variables in the specification, which have inhibitory activity of cytochrome P450RAI-I and P450RAI-2, and are suitable for the treatment of mammals with conditions that can be treated with retinoids, or that are controlled or They are sensitive to the body's native retinoic acid. Formulations containing the compounds of the invention can also be co-administered with retinoids and / or Vitamin A to enhance or prolong the effects of medications containing retinoids, Vitamin A, or the organism's native retinoic acid. |