abstract |
The present invention relates to triaryl-oxy-aryl-spiro-pyrimidine-2,4,6-trione metalloproteinase inhibitors of the formula (see formula I), wherein the X ring is a 5-7 membered heterocyclic ring , and where A, Y, B, G and W are as defined in the specification; and to pharmaceutical compositions and procedures for treating inflammation, cancers and other disorders. |