abstract |
The process consists of condensing (2-methyl- 6, 7, 8, 9-tetrahydro-4H-pyrido- [1,2-a] pyrimidin -3-yl] -acetaldehyde with 6-fluoro-3-piperidinyl) -1 , 2-benzisoxazole to obtain the intermediate enamine, vinyl} -2-methyl-6, 7, 8, 9-tetrahydro-pyrido - [1,2-a] pyrimidin-4- one followed by reduction of said enamine. |