| abstract |
Compounds of formula (1) in which R1 is hydroxy or NHSO2R1A wherein R1A is (C1-8) alkyl, cycloalkyl (C3-7) or {(C1-6) -cycloalkyl (C3) alkyl alkyl is described herein. -7)}, which are all optionally substituted two to 1 times with halo, cyano, nitro, O (C1-6) alkyl, amido, amino or phenyl, or R1A is C6 or C10 aryl which is optionally substituted 1 to 3 times with halo, cyano, nitro, (C1-6) alkyl, O-(C1-6) alkyl, amino or phenyl amido; R2 is cycloalkyl (C4-6); R3 is t-butyl or cycloalkyl (C5-6) and R4 is cycloalkyl (C4-6), or a pharmaceutically acceptable salt thereof. The compounds are useful as inhibitors of NS3-HCV Protease. |