| abstract |
The present invention provides 2,4-pyrimidinediamine compounds that inhibit IgE and / or IgG receptor signaling cascades that lead to the release of chemical mediators, intermediates and synthetic methods of compounds and methods for using the compounds in a variety of contexts, including in the treatment and prevention of diseases characterized by, caused by or associated with the release of chemical mediators by degranulation and other processes performed by activation of the IgE and / or IgG receptor signaling cascades. |