| abstract |
Novel useful cycloalkyl compound is described as inhibitors of potassium channel function (especially inhibitors of the KV1 subfamily of the K + channels that open with voltage, more especially the KV1.5 inhibitors that have been linked to the rectifier IKur current K + delayed ultra-rapid activation), methods of use of such compounds in the prevention and treatment of arrhythmia and conditions associated with IKur, and to pharmaceutical compositions containing such compounds. |