| abstract |
The invention relates to heterocyclic compounds consisting of a nucleus nitrogen atom surrounded by three pendant groups, wherein two of the three pendant groups are preferably benzimidazolylmethyl and tetrahydroquinolyl, and the third pendant group contains N and optionally contains additional rings; the compounds bind to chemokine receptors, including CXCR4 and CCR5, and demonstrate protective effects against infection of target cells by human immunodeficiency virus (HIV). |