abstract |
New methods for inhibiting angiogenesis and treating diseases associated with angiogenesis are described. The methods may consist of administering to an patient an effective amount of a 1,2-dithiol-3-thione derivative or a metabolite thereof. Preferred compounds for use in the methods include 5- (2-pyrazinyl) -4-methyl-1,2-dithiol-3-thione (Oltipraz) and its metabolites. |