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filingDate 2004-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_38e68ce2a8fd9ee8374a9f8aef0677a6
publicationDate 2005-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber MX-PA04002353-A
titleOfInvention POLYMORPHIC FORMS OF RIFAXIMINE, PROCEDURES FOR THEIR PRODUCTION AND USE OF THE SAME IN MEDICINAL PREPARATIONS.
abstract Polymorphic crystalline forms of the antibiotic rifaximin (INN) called rifaximin a and rifaximin? and a poorly crystalline form called rifaximin? These forms are useful in the production of medicinal preparations for oral and topical use and can be obtained by means of a crystallization process carried out by hot dissolution of the crude rifaximin in ethyl alcohol and by crystallization of the product by addition of water at a certain temperature and for a certain period of time. Crystallization is followed by drying carried out under controlled conditions until a specific water content is reached in the final product.
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type http://data.epo.org/linked-data/def/patent/Publication

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