| abstract |
The present invention is a multiparticulate tablet, which disintegrates in the mouth, which contains: i) a proton pump inhibitor, in particular of the benzimidazole type, in the form of enteric coated microgranules, these enteric coated granules have a additional coating with at least one barrier coating, such as for example a protective film based on methacrylic copolymer; ii) at least one antacid in the form of granules, for example based on CaCO3 and / or Mg (OH) 2 and / or A1 (OH) 3; and iii) a mixture of excipients comprising at least one disintegrating agent, a diluting agent, and a lubricant, and optionally a swelling agent, a permeability agent, sweeteners, flavorings and dyes, the present invention is directed to the processes for the elaboration of the tablet and its use in the treatment of gastrointestinal disorders. |