abstract |
(see formula) The invention relates to novel synthesis methods for the preparation of intermediates, which are suitable for the preparation of statin derivatives, especially with novel synthesis methods of the intermediate of formula VI where Ra and Rc are each one independently of the other, hydrogen or a hydroxy protecting group or together are a hydroxy protecting group, and Rb is a carboxy protecting group, whose methods are carried out by converting the intermediate of the formula XIX where Ra and Rc they are each independently of the other hydrogen or a hydroxy protecting group and Rb is a carboxy protecting group. |