| abstract |
Compounds represented by the following general formula (1), salts thereof, solvates thereof or N-oxides thereof: Q1-Q2-T0-N (R1) -Q3-N (R2) -T1-Q4 ( 1) where R1 and R2 each represent hydrogen, etc .; Q1 represents 5 or 6 saturated or unsaturated hydrocarbyl, etc., Q2 represents a single bond, etc .; Q3 represents the following group: (see formula) (where Q5 represents C1-C8 alkylene, etc.); and T0 and T1 each represent carbonyl, etc .; These compounds are useful as preventive and / or remedies for cerebral infarction, cerebral embolism, myocardial infarction, angina pectoris, pulmonary infarction, pulmonary embolism, Buerger's disease, deep venous thrombosis, disseminated intravascular coagulation, thrombosis after valve replacement or union, thrombosis and reocclusion after circulation reconstruction, systemic inflammatory response syndrome (SIRS), multiple organ dysfunction syndrome (MODS), extracorporeal circulation thrombosis, or blood clotting when blood is drawn. |