| abstract |
A compound represented by the following general formula, which has phosphodiesterase IV inhibitory activity; a use of the compound and an intermediate for it. (see formula) (I). (In the formula, R1 and R2 each is hydrogen, halogen, lower alkyl, lower alkoxy, etc .; R3 and R4 are each hydrogen, lower alkyl (substituted), halogen, etc .; R5 is hydrogen, lower alkyl, lower alkoxycarbonyl, etc .; and n is 0 or 1). R1, R2: hydrogen, a halogen, a lower alkyl, a lower alkoxy, or the like, R3 and R4: hydrogen, a lower (substituted) alkyl, a halogen, or the like, R5: hydrogen, a lower alkyl, a lower alkoxycarbonyl, or the like, and n: 0 or 1). |