abstract |
A preparation of inactivated influenza virus is described which comprises a stabilized hemagglutinin antigen in the absence of thiomersal, or at low levels of thiomersal, in which hemagglutinin is detectable by an SRb assay. The preparation of the Influenza virus may comprise a micelle modifying excipient, for example, a-tocopherol or a derivative thereof, in an amount sufficient to stabilize the hemagglutinin. |