| abstract |
The present invention is a pharmaceutical composition and method for controlling the release of a medication or vaccine to a patient where a slow, controlled release of medication or antigen occurs over a considerable period after the injection. The medicine or vaccine is contained in sugar glass rhinospheres and then placed in an anhydrous liquid, preferably perfluorocarbon, so that the vaccine is protected against dissolution while remaining surrounded by the anhydrous liquid. This simple non-toxic system, deliverable by current syringe or present or future needle-free systems, is not expensive and is reliable and helps in the delivery of parenteral medication or mass immunization hoods by reducing the need for repeated injections. |