| abstract |
Compounds of formula (I) are provided: (see formula) wherein R1, R2, R3, R4, R5, R6, T, W, X, Y and Z are as defined herein, together with salts, hydrates and / or pharmaceutically acceptable prodrugs thereof; Methods of using these compounds to inhibit the production of beta-amyloid and for the treatment of Alzheimer's disease and Down syndrome are described. |