| abstract |
The present invention relates to inhibitors of p38, a mammalian protein kinase involved in cell proliferation, cell death and the response to extracellular stimuli. The invention is also related to ZAP70 inhibitors. The invention also relates to methods of producing these inhibitors. The invention also provides pharmaceutical compositions comprising the inhibitors of the invention and methods for using those compositions in the treatment and prevention of various disorders. These compounds have the general formula: (Ia) (Ib) (Ic) and (Id). |