| abstract |
A multi-valent vaccine composition is described comprising a conjugate of the capsular polysaccharide of H.influenzae b not absorbed in an aluminum adjuvant salt, and two or more additional bacterial polysaccharides. Also described is a multi-valent vaccine composition comprising a component of whole cell pertussis, tetanus toxoid, diphtheria toxoid, Hepatitis B surface antigen, a conjugate of H.fluenzae b capsular polysaccharide, and a conjugate of a capsular polysaccharide of N.meningitidis type A or C (or both). In addition, a multi-valent vaccine composition is described which comprises a whole cell pertussis component, tetanus toxoid, diphtheria toxoid, and a low dose of a H.influenzae capsular polysaccharide b conjugate. |